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Vaginal care is the new skin care

Over 85% of women experience vaginal dryness, urgency, frequent
UTIs & painful sex.
Get relief with vaginal estrogen, an FDA-approved treatment that's safe for nearly every woman to use.
Join now
Cream bottles
Cream
Get Free vaginal estrogen cream* (worth up to $480/year) with a multi-month membership
*Must medically qualify and be on a 3-or-12-month plan
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What is vaginal estrogen?

white Cream tube

What is vaginal estrogen?

Vaginal estrogen cream is a localized form of hormone therapy that can help treat AND prevent these symptoms and can be safe for almost any woman to use.
Get care today
Don’t just accept it

Feeling better is more than possible.

Our results
90%

of Evernow members report symptom improvement within 2 months*

*Data found from Evernow members

90%

of Evernow members report symptom improvement within 2 months*

*Data found from Evernow members

How our price compares

Get care today
Get care today

What vaginal estrogen treats

Urinary
discomfort peeing
Genital symptoms
vaginal dryness
Sexual health
painful sex, reduced orgasm
Physical
tissue decline
Healthy microbiome
frequent UTI’s

Membership plans

Most flexible
Monthly
$49/month
$49 billed every month
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Most popular
3-month
Save 12%
$43/month
$129 billed every 3 months
Free vaginal estrogen cream* ($120 value)
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Best value
12-month
Save 28%
$35/month
$420 billed every 12 months
Free vaginal estrogen cream* ($480 value)
Get care today

FAQs

What is vaginal estradiol (estrogen) cream?

Vaginal estradiol cream is a prescription medication designed for localized use in the vaginal area to treat symptoms associated with genitourinary syndrome of menopause (GSM). These include vaginal atrophy, vaginal dryness, itching, painful intercourse and other urinary complaints commonly associated with menopause.

How does vaginal estradiol cream work?

Vaginal estradiol cream belongs to the drug class of estrogen hormones and is designed to deliver estradiol directly to the vaginal tissues. It works by helping to replenishing estrogen levels in that area, thereby restoring vaginal moisture, improving the health of the vaginal lining, and alleviating symptoms of vaginal atrophy often associated with menopause.

How do you use vaginal estrogen cream?

The cream comes with an applicator that you fill up and insert into your vagina. You can also split the dose of estrogen cream between the inside and entryway to your vagina, including on and around your urethra and clitoris. 

Use the cream twice a week. We recommend doing so right before bed, as this allows the cream to absorb.

When should I expect to see results with vaginal estradiol cream?

The time it takes for vaginal estradiol cream to alleviate menopausal symptoms, like vaginal dryness and painful sex, can vary from person to person. Many women report experiencing relief within a few weeks of starting treatment, while others may take longer to notice a significant improvement. It's essential to discuss expectations and progress with your Evernow provider, as the response to estradiol can differ based on individual factors and the specific symptoms being addressed.

What is the typical dosage of vaginal estradiol cream?

Dosage of vaginal estradiol cream for menopausal symptom management varies depending on the brand and the individual's needs. Typically, dosing involves applying a small amount (usually around 1 gram) to the vaginal area, once or twice a week. Your exact dosage will be determined by your Evernow provider based on your specific needs and response to the treatment. It is important to adhere to the prescribed dosage and schedule provided by your Evernow provider.

How do I know if vaginal estradiol cream for menopause symptoms is right for me?

To determine if vaginal estradiol cream is appropriate for you in managing vaginal symptoms of menopause, consult with your Evernow provider. They will consider your specific symptoms, medical history, and overall health to help you make an informed decision and discuss potential risks and benefits.

What are possible side effects of vaginal estradiol cream?

Vaginal estradiol cream, like any medication, can cause side effects. Common side effects of vaginal estradiol cream used for hormone replacement therapy during menopause, may include local irritation and discharge. Serious side effects are rare but can include allergic reactions. Consulting your Evernow provider about any concerns or side effects is crucial for appropriate management and evaluation of the treatment's safety.

Which vaginal estradiol creams do you prescribe?

Our providers prescribe both branded and generic forms of the estradiol patch based on your needs, insurance coverage and preferences. We currently offer generic Estrace or a compounded form of estradiol cream. If you have specific preferences or concerns regarding your medications, please raise them with your Evernow provider.

Should I consider pelvic floor exercises in addition to vaginal estrogen cream?

Pelvic floor exercises help with stress incontinence and sexual discomfort. They strengthen muscles and can complement vaginal estrogen. Find targeted exercises on Evernow's Learn platform.

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